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X-WR-CALDESC:Events for Department of Chemical Engineering
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DTSTART;TZID=America/New_York:20240917T100000
DTEND;TZID=America/New_York:20240917T143000
DTSTAMP:20260414T124531
CREATED:20240722T180020Z
LAST-MODIFIED:20240722T180020Z
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SUMMARY:Chemical Engineering Research Showcase
DESCRIPTION:Join us for our Annual Chemical Engineering Research Showcase in the Cabral Center! Every year\, our Chemical Engineering PhD students and select faculty members present their work at the Research Showcase in the form of Oral Presentations\, Poster Sessions\, and 5-minute Presentations. All are welcome to attend.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-research-showcase/
LOCATION:The Cabral Center\, 40 Leon Street\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240911T090000
DTEND;TZID=America/New_York:20240911T110000
DTSTAMP:20260414T124531
CREATED:20240903T135736Z
LAST-MODIFIED:20240903T135736Z
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SUMMARY:ChE PhD Dissertation Defense: Ronodeep Mitra
DESCRIPTION:Name:\nRonodeep Mitra \nTitle: \nGlycocalyx Therapy to Restore Anti-Atherosclerotic Endothelial Cell Function \nDate:\n9/11/2024 \nTime:\n9:00:00 AM \nCommittee Members:\nProf. Eno Ebong (Advisor)\nProf. Mansoor Amiji\nProf. Rebecca Carrier\nProf. Arthur J. Coury\nProf. Jessica M. Oakes \nLocation:\nEXP 610 and Zoom \nAbstract:\nThe endothelial cell (EC) glycocalyx (GCX) is a negatively charged complex sugar-rich layer that lines the endothelium. It is an important contributor to the physical and biochemical health of the vasculature and endothelium\, while mediating mechanotransduction and vascular signaling. For example\, when exposed to physiological (unidirectional and uniform in magnitude) levels of shear stress from the mechanical force of blood flow\, the GCX is abundant and aids in the production of vasodilator nitric oxide (NO)\, which regulates vascular tone. Furthermore\, the dynamics of the flow-regulated GCX determine the structural integrity of connexin proteins that comprises interendothelial gap junctions and control the flow of communication between neighboring ECs. Finally\, the GCX acts as a physical barrier to numerous components in circulating blood\, including low-density lipoproteins (LDLs) and inflammatory cells such as monocytes that differentiate into macrophages and platelets. \nLoss of the EC GCX can be attributed to disturbed vasculature blood flow patterns. This condition renders the endothelium as adhesive and permeable\, resulting in infiltration of the vessel walls by blood circulating LDLs\, compromising active EC-EC communication via interendothelial gap junctions\, and reduction in NO production\, leading to vasoconstriction. These phenotypes lead to vascular dysfunction\, atherosclerosis\, and other serious secondary cardiovascular events\, such as myocardial infarctions and strokes. Hence\, we propose either repurposing therapies that were\nnot originally indicated for GCX therapy or the development of novel GCX therapies and hypothesize that targeting the EC GCX will restore vascular function and prevent further downstream cardiovascular events\, such as atherosclerosis. \nWe first tested our hypothesis by assessing the efficacy of repurposing diosmin\, a flavanone glycoside of diosmetin\, which is a nutraceutical used to currently treat chronic venous insufficiency. Previous studies have shown diosmin’s potent anti-inflammatory and anti-oxidant properties on the endothelium. Hence\, we wanted to determine if diosmin would repair mechanically damaged endothelial GCX in regions of disturbed flow (DF) patterns and restore anti-atherosclerotic endothelium mechanotransduction function. For this study\, we utilized a unique murine in vivo DF model\, where the left carotid artery (LCA) is partially ligated\, while the right carotid artery (RCA) is not surgically intervened and was the designated uniform flow (UF) control for each mouse. Diosmin treatment elevated activated endothelial NO synthase level (p-eNOS)\, inhibited inflammatory cell uptake\, decreased vessel wall thickness and increased vessel diameter\, and increased GCX coverage on the endothelium in ligated LCA. This corroborated support that diosmin protects endothelial GCX integrity and preserves complex endothelial function. \nNext\, in vitro and in vivo DF models were used to assess a novel therapy\, combining sphingosine-1-phosphate (S1P)\, a bioactive lipid mediator\, and heparin in regenerating the endothelial GCX. We used a parallel-plate flow chamber to simulate flow conditions in vitro on human coronary arterial endothelial cells (HCAECs) and a partial carotid ligation murine model to mimic DF in vivo\, as mentioned above. In vitro data showed that heparin/S1P therapy improved the function of DF-conditioned ECs by restoring the GCX and promoting EC alignment and elevated p-eNOS expression. Furthermore\, heparin/S1P treatment restored GCX in the LCA\, enhancing GCX thickness and coverage of the blood vessel wall and reducing vessel wall thickness\, demonstrating advances in a novel therapeutic that regenerates EC GCX and restores complex vascular function in DF conditions. \nThis research work is an excellent step towards the development of repurposed or novel therapeutics that can be applied to replace\, stabilize\, or protect the GCX and restore GCX-mediated EC mechanotransduction\, particularly in DF conditions. These prospective mechano-therapeutics could represent breakthrough solutions for preventing cardiovascular diseases such as atherosclerosis in the future.
URL:https://che.nucoe.madebyvital.com/event/che-phd-dissertation-defense-ronodeep-mitra/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240701T130000
DTEND;TZID=America/New_York:20240701T150000
DTSTAMP:20260414T124531
CREATED:20240618T150504Z
LAST-MODIFIED:20240618T150504Z
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SUMMARY:ChE PhD Dissertation Defense: Mohammad Hamrangsekachaee
DESCRIPTION:PhD Dissertation Defense: Endothelial Glycocalyx: Response to Fluid and Solid Mechanics in its Environment \nMohammad Hamrangsekachaee \nLocation: Snell Library 033 and Zoom \nAbstract: Atherosclerosis\, a precursor to cardiovascular diseases (CVDs)\, accounts for 37% of deaths in individuals under 70 years old\, primarily due to endothelial cell (EC) dysfunction. The glycocalyx (GCX)\, a carbohydrate-rich structure on ECs lining the vessel luminal surface\, is crucial for EC function and vascular health by regulating vascular tone\, hemostasis\, permeability\, and mechanotransduction. Therefore\, cellular models emulating the vascular mechanical environment are vital for understanding GCX’s role and its interaction with mechanical surroundings. This dissertation introduces an innovative in vitro model to investigate the combined effects of tissue stiffness and shear stress on endothelial cell function. \nTunable non-swelling gelatin-methacrylate (GelMA) hydrogels were fabricated with stiffnesses of 2.5 and 5 kPa\, representing healthy vessel tissues\, and 10 kPa\, corresponding to diseased vessel tissues. Immunocytochemistry analysis showed that on hydrogels with different levels of stiffness\, the GCX’s major polysaccharide components exhibited dysregulation in distinct patterns. For example\, there was a significant decrease in heparan sulfate expression on pathological substrates (10 kPa)\, while sialic acid expression increased with increased matrix stiffness. \nGelMA hydrogels were then integrated into a flow chamber designed to generate physiological flow conditions. The combined effects of fluid shear stress and substrate stiffness were analyzed for heparan sulfate\, sialic acid\, hyaluronic acid\, syndecan-1\, CD44\, and YAP. Under shear stress\, heparan sulfate’s coverage was reduced at 10 kPa\, while sialic acid and CD44 expression increased at 10 kPa. YAP activation\nshowed increased nuclear translocation and decreased phosphorylation at 10 kPa. Our findings revealed that substrate stiffness and mechanical forces significantly influence GCX expression and endothelial cell function. \nThis research highlights the critical role of the mechanical environment on GCX in vascular health\, particularly in the context of atherosclerosis. By developing an innovative in vitro model that integrates tissue rigidity and shear stress\, we have provided a more precise simulation of the vascular environment. This model offers a valuable tool for further understanding EC mechanotransduction and developing targeted treatments for cardiovascular diseases.
URL:https://che.nucoe.madebyvital.com/event/che-phd-dissertation-defense-mohammad-hamrangsekachaee/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240624T120000
DTEND;TZID=America/New_York:20240624T130000
DTSTAMP:20260414T124531
CREATED:20240617T134559Z
LAST-MODIFIED:20240617T134559Z
UID:4984-1719230400-1719234000@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Summer Sustainability Seminar Series: Ewa Marek
DESCRIPTION:Chemical looping for sustainable production of chemicals \nThe chemical industry is centred on the processing of crude oil and is responsible for the lion’s share of greenhouse gas emissions. Running industrial-scale installations requires huge energy inputs\, employing high temperatures\, pressures\, and\, often\, explosive mixtures. The current industry is designed to work continuously\, using cheap\, petrochemical feedstock. Switching the starting point and moving from oil to renewable feedstock\, whether it is bio-derived carbonaceous material\, captured CO2\, or renewable electricity\, requires new decentralised and flexible operations\, as all these resources are spatially distributed and available intermittently. Our work focuses on small-scale\, dynamic processes\, developing and employing new reaction and process pathways to produce key chemicals. This talk will present our work using a chemical looping approach where solid particles of metal oxides are the sole source of oxygen to catalytic reactions. In particular\, I will discuss the chemical looping epoxidation (CL-E) of ethylene to produce ethylene oxide (EO) and chemical looping oxidative dehydrogenation (CL-ODH) of ethanol to produce acetaldehyde. \n\nBio \nDr. Ewa Marek is an associate professor at the Department of Chemical Engineering and Biotechnology\, University of Cambridge and a fellow of Jesus College. She leads the Energy Reactions and Carriers Group\, working on the production of value-added chemicals from intermittently available renewable feedstock and electricity\, incorporating non-thermal plasma\, ultrasounds and chemical looping to drive efficient\, transient processes. This work led to 2021 Hinshelwood Prize and 2023 Energy&Fuels Rising Star Award for early-career academics. Before setting up her group\, she was a post-doctoral associate in the Engineering Department\, Cambridge\, and earlier\, she worked for six years on industrial R&D and advanced measurement methods in the UK\, Netherlands and Poland. She studied energy and chemical processing (BEng\, MSc) in Cracow and carbon capture (PhD) in Katowice (both in Poland). \nLinks \nhttps://www.ceb.cam.ac.uk/staff/dr-ewa-marek \nhttps://www.jesus.cam.ac.uk/people/ewa-marek
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-summer-sustainability-seminar-series-ewa-marek/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240613T090000
DTEND;TZID=America/New_York:20240613T110000
DTSTAMP:20260414T124531
CREATED:20240611T191401Z
LAST-MODIFIED:20240611T191401Z
UID:4975-1718269200-1718276400@che.nucoe.madebyvital.com
SUMMARY:ChE PhD Dissertation Defense: Ian Smith
DESCRIPTION:PhD Dissertation Defense: A Primary Intestinal Model to Assay Lymphatic Drug Transport \nIan Smith \nLocation: Dodge Hall 070 & Zoom \nAbstract: Lipophilic drugs (logP > 5) often fail to develop as commercial oral medications due to poor absorption\, distribution\, metabolism\, excretion and/or toxicity (ADMET) properties. Beyond-rule-of-5 (bro5) candidate attrition in the clinic may be relieved by targeted delivery to chylomicrons (CMs) as chaperones into the mesenteric lymphatics. Lymph-cannulated animal models that estimate lymphatic bioavailability (F%) are surgically challenging\, costly and highly variable between species. In vitro models of the human intestinal epithelium can preserve enterocyte-like CM assembly and thereby recapitulate on the benchtop drug intercalation with CM components during transcytosis (i.e. the “lymphatic permeability” mechanism). This thesis proposes primary small intestinal epithelia as alternative platforms to the Caco-2 Transwell® culture for assaying lymphatic drug transport. \nPrimary monolayers cultured from small intestinal enteroids were investigated for CM synthesis\, secretion\, and transport of lymphotropic small molecules. The specific aims were to: 1) establish a mixed bile micelle formulation compatibile with primary cultures\, 2) develop a first-principle mathematical description of poorly water-soluble drug (PWSD) partitioning and uptake from lipid-containing micelles\, 3) characterize apolipoprotein B (apoB)-containing lipoprotein secretion from primary cultures along an oleic acid (OA)/2-monoloein (2-MO) stimulation axis\, and 4) compare CM-transported drug in culture to lymph-cannulated F% estimations. Exposure of mixed bile micelles containing 4:1 taurocholate (TC) and phosphatidylcholine (PC) to the brush border membrane of human duodenum (hDuo) and Caco-2/HT29-MTX co-cultures (Co-C) compromised tight junctional resistance and paracellular permeability in Co-C above 5 mM TC whereas hDuo were unaffected. Permeability measurements in the Co-C monolayer showed PWSD transport from TC/PC micelles to be reasonably predicted by changes in the apical (i.e. lumen-side) free or total drug concentration (CD\,free or CD\,total)\, but extent of fatty acid (FA)-induced supersaturation was limited by lipo-toxicity. Over a time course aligned to the window of lymph triglyceride (TG) turnover in vivo (i.e. 6 hours)\, controlled 2-monooloein (2-MO) stimulation of hDuo and murine ileum (mIle) monolayers induced significant increases in TG mass (~3.5-fold) and particle diameter (Dh) (~2-fold) of  < 1.006 g/mL lipoproteins. Primary enterocytes upregulated mgat2 transcription in the presence of 2-MO substrate to indicate that TG output in these FBS-differentiated cultures engaged the sn-1\,2-monoglyceride (2-MG) re-esterification pathway. Organoid cultures also favored basal-polarized apoB-48 release distinct from the bidirectional apoB-100 output of Caco-2. Finally\, apparent permeability of halofantrine (Hf; logP 7.34; BCS Class II) and navitoclax (Nx; logP 7.93; BCS Class IV) in CMs secreted from mIle but not Caco-2 were increased from TC/PC control conditions by inclusion of +OA/2-MO in micelles. For Hf\, the fraction of dose absorbed by CMs (faCM = 6.8 ± 0.9%) was similar to the fraction of dose transported into the lymph of cannulated rats (falymph = 5.5 ± 0.8%). \nDevelopment of an in vitro-in vivo correlation between lymph-cannulated animals and the primary transport assay developed herein might assist preclinical programs in translating lipid-based oral modalities to humans. Expansion of the organoid donor set (by species and small intestinal region)\, combinatorial probing of more lipid stimulation axes (by substrate chain length and saturation)\, and scaling of monolayer culture could refine the lymphatic assay into a high-throughput screen. Beyond a drug delivery context\, de novo CM assembly in enterocytes that retain a native small intestinal phenotype enables closed-system study of outstanding questions regarding intestinal lipoprotein formation and dyslipidemia disease intervention.
URL:https://che.nucoe.madebyvital.com/event/che-phd-dissertation-defense-ian-smith/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240426T120000
DTEND;TZID=America/New_York:20240426T130000
DTSTAMP:20260414T124531
CREATED:20240423T204036Z
LAST-MODIFIED:20240423T204036Z
UID:4871-1714132800-1714136400@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Dr. David Brayden
DESCRIPTION:Oral administration of peptides: The quest to improve bioavailability \nThe oral administration of peptides and proteins remains one of the great challenges in pharmaceutical science. Efficacy depends on patients committing to take essential medicines and this is built upon the convenience of a dosing regimen using a patient-friendly route of administration. Large molecules have problems negotiating the GI tract to achieve systemic delivery due to instability against metabolizing enzymes and low permeability across the epithelium. To date\, just five linear peptides aimed at systemic delivery have been approved by the FDA\, the most recent being oral semaglutide (Rybelsus®\, Novo Nordisk\, 2019) and oral octreotide (Mycappsa®\, Chiasma Ltd\, 2020). These approvals heralded a renewed interest in the field\, built around developing Glucagon-1-like peptide 1 (GLP-1) mimetics for Type II diabetes and obesity\, alone or as a dual agonist with other gut peptides. Relative success to date for oral peptides has been achieved with standard oral dosage forms made with permeation enhancers\, but these will only work for niche peptides with high potency and long half-lives. \nMy group has been working on the mechanism of action of the intestinal permeation enhancers that typically are used to enable these formulations\, albeit that oral bioavailability with the above products is less than 1%. We have focussed on comparisons between sodium caprate and SNAC\, both medium-chain fatty acid derivatives\, and found that they have multimodal actions suggesting a dual effects on tight junctions and the intestinal epithelial plasma membrane depending on the concentration and the bioassay. We also have contributed to the search for other permeation enhancers (alone and combination) that can be used with peptides in oral dosage forms including the Gattefosse excipients\, Labrasol® and Labrafac™. We are working on a nanotechnology concept\, where we have achieved 7% bioavailability for insulin in a rat model using a core-shell construct based on silica coating over a core of peptide and the excipients\, L-arginine\, and zinc. Finally\, devices may eventually be able to increase the oral bioavailability of peptides by an order of magnitude over permeation enhancers according to data from animal models\, but clinical testing is at an early stage and the toxicology and the regulatory pathway for these types of technologies have yet to be addressed. I will touch on aspects and examples of these multiple approaches in my talk at Northeastern. \n\nDavid Brayden is Full Professor of Advanced Drug Delivery at the School of Veterinary Medicine and a Fellow of the UCD Conway Institute. Following a Ph.D. in Pharmacology at the University of Cambridge\, UK (1989)\, and a post-doctoral research fellowship at Stanford University\, CA (1991)\, he set up Elan Corporation’s pharmacology laboratory in Dublin (1991). At Elan\, he became a senior scientist and project manager of several of Elan’s Joint-Venture drug delivery research collaborations with US biotech companies. In 2001\, he joined UCD as a college lecturer in veterinary pharmacology and was appointed Senior Lecturer (2005)\, Associate Professor (2006)\, and Full Professor (2014). He completed a successful Principle Investigator Grant from SFI on the topic of oral delivery of novel mucoadhesive polymeric peptide conjugates (2005-2009). Professor Brayden was the Director of an SFI Research Cluster grant (The Irish Drug Delivery Research Network)\, that was awarded 7.2 million euro by SFI from 2007-2013. He was the Deputy Coordinator of an EU 7th Framework grant on oral nanomedicines (www.TRANS-INT.eu)\, 2012-2017. In 2014\, he was one of four Principal Investigators (Co-PIs) on the successful SFI Centre bid in Medical Devices (CURAM)\, worth over 40 million EUR over 6 years\, which was renewed for 6 years in 2021. He is the coordinator of the Horizon Europe consortium grant\, BUCCAL-PEP\, which was awarded 4m EUR and runs from 2022-2026. He is the author or co-author of more than 300 research publications and patents. Professor Brayden serves on the Editorial Advisory Boards of Drug Discovery Today\, Advanced Drug Delivery Reviews and the Journal of Veterinary Pharmacology and Therapeutics. In 2021 he was appointed Chief Editor of “Frontiers in Drug Delivery”. He was Chairman of the UK-Ireland Chapter of the Controlled Release Society (2003-2006)\, Co-Chair of the Veterinary Programmes at the CRS international conferences (2003-2006)\, and served on the CRS Board of Scientific Advisors (2006-2009) and the CRS Annual Meeting Programme Committee (2015\, 2016). At UCD\, he was Chairman of the Animal Research Ethics Committee (2005-2007) and was a member of the UCD Research Ethics Committee (2006-2011) and was elected by Academic Council to the UCD Promotions and Tenure Committee (2010-2012) and to the UCD Academic Council for Academic Centres Committee\, ACCAC (2019-). He was Director of Research for the School of Agriculture\, Food Science and Veterinary Medicine (2007-2008) and Head of the Veterinary Biosciences Section from 2013-2017. On the teaching side\, he coordinates undergraduate and postgraduate modules on Biological Fluids and Drug Discovery and Development and contributes to a module on Cell Communication. He contributes Professional Ethics material to the Conway Institute Core Research Skills modules and also coordinates a 4th level online module on Drug Discovery and Development. In 2015\, he was made an Adjunct Professor at NUI Galway to support his Co-PI role in the SFI CURAM Centre. He was elected as a Fellow of both the Controlled Release Society (2012) and the American Association of Pharmaceutical Scientists (2017). In 2021\, he was appointed by the Minister of Health to the National Research Ethics Committee (Clinical Trials A). He acts as a consultant to selected Pharma and Biotech companies.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-dr-david-brayden/
LOCATION:024 East Village\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240417T133000
DTEND;TZID=America/New_York:20240417T143000
DTSTAMP:20260414T124531
CREATED:20240405T163435Z
LAST-MODIFIED:20240405T212745Z
UID:4834-1713360600-1713364200@che.nucoe.madebyvital.com
SUMMARY:Soft Matter Days
DESCRIPTION:Soft Matter Days: April 8-17\, will feature invited guest speakers discussing a variety of interdisciplinary topics in soft matter and complex fluids.  These topics sit at the interface of chemical & mechanical engineering\, materials science\, physics\, chemistry\, and biology.  Guest speakers will discuss real-world phenomena found in food\, blood flow\, and granular materials.  Two talks are guest lectures in CHME5179: RSVP required for those not in the class. \nMonday\, April 8\, 2:15pm\, Curry 340\nCapillary Rise and Thin Films Near Edges: New Insights from Self-similarity\nHoward Stone\, Princeton University\nHost: Xiaoyu Tang x.tang@northeastern.edu \nTuesday\, April 9\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\n“Complex Fluids & Soft Matter in Food”\nDave Weitz\, Harvard University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nThursday\, April 11\, 1:30pm\, HS 210\nDynamics of blood flow at the cellular level in health and disease\nMichael Graham\, University of Wisconsin\nHost: Sara Hashmi s.hashmi@northeastern.edu \nFriday\, April 12\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\nNonlinear Rheology of Complex Fluids: Exploring Microstructure\nKate Honda\, Northeastern University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nWednesday\,  April 17\, 1:30pm\, HS 210\nUniversality and scaling in shear thickening suspensions\nBulbul Chakraborty\, Brandeis University\nHost: Sara Hashmi s.hashmi@northeastern.edu
URL:https://che.nucoe.madebyvital.com/event/soft-matter-days-2024-04-17/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240412T095000
DTEND;TZID=America/New_York:20240412T113000
DTSTAMP:20260414T124531
CREATED:20240405T163435Z
LAST-MODIFIED:20240405T212744Z
UID:4840-1712915400-1712921400@che.nucoe.madebyvital.com
SUMMARY:Soft Matter Days
DESCRIPTION:Soft Matter Days: April 8-17\, will feature invited guest speakers discussing a variety of interdisciplinary topics in soft matter and complex fluids.  These topics sit at the interface of chemical & mechanical engineering\, materials science\, physics\, chemistry\, and biology.  Guest speakers will discuss real-world phenomena found in food\, blood flow\, and granular materials.  Two talks are guest lectures in CHME5179: RSVP required for those not in the class. \nMonday\, April 8\, 2:15pm\, Curry 340\nCapillary Rise and Thin Films Near Edges: New Insights from Self-similarity\nHoward Stone\, Princeton University\nHost: Xiaoyu Tang x.tang@northeastern.edu \nTuesday\, April 9\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\n“Complex Fluids & Soft Matter in Food”\nDave Weitz\, Harvard University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nThursday\, April 11\, 1:30pm\, HS 210\nDynamics of blood flow at the cellular level in health and disease\nMichael Graham\, University of Wisconsin\nHost: Sara Hashmi s.hashmi@northeastern.edu \nFriday\, April 12\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\nNonlinear Rheology of Complex Fluids: Exploring Microstructure\nKate Honda\, Northeastern University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nWednesday\,  April 17\, 1:30pm\, HS 210\nUniversality and scaling in shear thickening suspensions\nBulbul Chakraborty\, Brandeis University\nHost: Sara Hashmi s.hashmi@northeastern.edu
URL:https://che.nucoe.madebyvital.com/event/soft-matter-days-2024-04-12/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240411T133000
DTEND;TZID=America/New_York:20240411T143000
DTSTAMP:20260414T124531
CREATED:20240405T163435Z
LAST-MODIFIED:20240405T212744Z
UID:4838-1712842200-1712845800@che.nucoe.madebyvital.com
SUMMARY:Soft Matter Days
DESCRIPTION:Soft Matter Days: April 8-17\, will feature invited guest speakers discussing a variety of interdisciplinary topics in soft matter and complex fluids.  These topics sit at the interface of chemical & mechanical engineering\, materials science\, physics\, chemistry\, and biology.  Guest speakers will discuss real-world phenomena found in food\, blood flow\, and granular materials.  Two talks are guest lectures in CHME5179: RSVP required for those not in the class. \nMonday\, April 8\, 2:15pm\, Curry 340\nCapillary Rise and Thin Films Near Edges: New Insights from Self-similarity\nHoward Stone\, Princeton University\nHost: Xiaoyu Tang x.tang@northeastern.edu \nTuesday\, April 9\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\n“Complex Fluids & Soft Matter in Food”\nDave Weitz\, Harvard University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nThursday\, April 11\, 1:30pm\, HS 210\nDynamics of blood flow at the cellular level in health and disease\nMichael Graham\, University of Wisconsin\nHost: Sara Hashmi s.hashmi@northeastern.edu \nFriday\, April 12\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\nNonlinear Rheology of Complex Fluids: Exploring Microstructure\nKate Honda\, Northeastern University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nWednesday\,  April 17\, 1:30pm\, HS 210\nUniversality and scaling in shear thickening suspensions\nBulbul Chakraborty\, Brandeis University\nHost: Sara Hashmi s.hashmi@northeastern.edu
URL:https://che.nucoe.madebyvital.com/event/soft-matter-days-2024-04-11/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240410T120000
DTEND;TZID=America/New_York:20240410T130000
DTSTAMP:20260414T124531
CREATED:20240328T155531Z
LAST-MODIFIED:20240328T155531Z
UID:4827-1712750400-1712754000@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Dr. Jodie Lutkenhaus
DESCRIPTION:Organic Batteries for a More Sustainable Future \nCobalt\, nickel\, and lithium are essential ingredients in today’s lithium-ion batteries (LIBs)\, but their continued use presents economic\, ethical\, and environmental challenges. Society must now begin to consider the implications of a LIB’s full life cycle\, including the carbon footprint\, the economic and environmental costs\, and material access. These challenges motivate the case for degradable or recyclable batteries sourced from earth-abundant materials whose life cycle bears minimal impact on the environment. This presentation considers organic polymer-based batteries\, which have the potential to address many of these issues. Redox-active polymers form the positive and negative electrodes\, storing charge through a reversible redox mechanism. We demonstrate polypeptide radical batteries that degrade on command into amino acids and by-products as a first step toward circular organic batteries. Further\, we show the recycling of redox-active polymer electrodes using a solvent-based approach. Polymer-air batteries are examined as high-capacity alternatives to metal-air batteries. The molecular mechanism for each case is investigated\, revealing pathways forward for improving each polymer’s performance. Taken together\, organic batteries offer the promise of a circular platform free of critical elements. \n\nJodie L. Lutkenhaus is a Professor\, Associated Department Head\, and holder of the Axalta Chair in the Artie McFerrin Department of Chemical Engineering at Texas A&M University. Lutkenhaus received her B.S. in 2002 from The University of Texas at Austin and her Ph.D in 2007 from the Massachusetts Institute of Technology. Current research areas include polyelectrolytes\, redox-active polymers\, energy storage\, and composites. She has received recognitions including World Economic Forum Young Scientist\, Kavli Fellow\, NSF CAREER\, AFOSR Young Investigator\, and the 3M Non-tenured Faculty Award. She is the past-Chair of the AICHE Materials Engineering & Sciences Division. Lutkenhaus is the Deputy Editor of ACS Applied Polymer Materials and a member of the U.S. National Academies Board of Chemical Sciences & Technology.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-dr-jodie-lutkenhaus/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240409T095000
DTEND;TZID=America/New_York:20240409T113000
DTSTAMP:20260414T124531
CREATED:20240405T163435Z
LAST-MODIFIED:20240405T212744Z
UID:4836-1712656200-1712662200@che.nucoe.madebyvital.com
SUMMARY:Soft Matter Days
DESCRIPTION:Soft Matter Days: April 8-17\, will feature invited guest speakers discussing a variety of interdisciplinary topics in soft matter and complex fluids.  These topics sit at the interface of chemical & mechanical engineering\, materials science\, physics\, chemistry\, and biology.  Guest speakers will discuss real-world phenomena found in food\, blood flow\, and granular materials.  Two talks are guest lectures in CHME5179: RSVP required for those not in the class. \nMonday\, April 8\, 2:15pm\, Curry 340\nCapillary Rise and Thin Films Near Edges: New Insights from Self-similarity\nHoward Stone\, Princeton University\nHost: Xiaoyu Tang x.tang@northeastern.edu \nTuesday\, April 9\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\n“Complex Fluids & Soft Matter in Food”\nDave Weitz\, Harvard University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nThursday\, April 11\, 1:30pm\, HS 210\nDynamics of blood flow at the cellular level in health and disease\nMichael Graham\, University of Wisconsin\nHost: Sara Hashmi s.hashmi@northeastern.edu \nFriday\, April 12\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\nNonlinear Rheology of Complex Fluids: Exploring Microstructure\nKate Honda\, Northeastern University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nWednesday\,  April 17\, 1:30pm\, HS 210\nUniversality and scaling in shear thickening suspensions\nBulbul Chakraborty\, Brandeis University\nHost: Sara Hashmi s.hashmi@northeastern.edu
URL:https://che.nucoe.madebyvital.com/event/soft-matter-days-2024-04-09/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240408T141500
DTEND;TZID=America/New_York:20240408T143000
DTSTAMP:20260414T124531
CREATED:20240405T203435Z
LAST-MODIFIED:20240405T212740Z
UID:4832-1712585700-1712586600@che.nucoe.madebyvital.com
SUMMARY:Soft Matter Days
DESCRIPTION:Soft Matter Days: April 8-17\, will feature invited guest speakers discussing a variety of interdisciplinary topics in soft matter and complex fluids.  These topics sit at the interface of chemical & mechanical engineering\, materials science\, physics\, chemistry\, and biology.  Guest speakers will discuss real-world phenomena found in food\, blood flow\, and granular materials.  Two talks are guest lectures in CHME5179: RSVP required for those not in the class. \nMonday\, April 8\, 2:15pm\, Curry 340\nCapillary Rise and Thin Films Near Edges: New Insights from Self-similarity\nHoward Stone\, Princeton University\nHost: Xiaoyu Tang x.tang@northeastern.edu \nTuesday\, April 9\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\n“Complex Fluids & Soft Matter in Food”\nDave Weitz\, Harvard University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nThursday\, April 11\, 1:30pm\, HS 210\nDynamics of blood flow at the cellular level in health and disease\nMichael Graham\, University of Wisconsin\nHost: Sara Hashmi s.hashmi@northeastern.edu \nFriday\, April 12\, 9:50am\, Zoom (Guest Lecture for CHME 5179)\nNonlinear Rheology of Complex Fluids: Exploring Microstructure\nKate Honda\, Northeastern University\nRSVP: Sara Hashmi s.hashmi@northeastern.edu \nWednesday\,  April 17\, 1:30pm\, HS 210\nUniversality and scaling in shear thickening suspensions\nBulbul Chakraborty\, Brandeis University\nHost: Sara Hashmi s.hashmi@northeastern.edu
URL:https://che.nucoe.madebyvital.com/event/soft-matter-days/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240403T120000
DTEND;TZID=America/New_York:20240403T130000
DTSTAMP:20260414T124531
CREATED:20240326T142857Z
LAST-MODIFIED:20240326T142857Z
UID:4824-1712145600-1712149200@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Dr. Sindia M. Rivera Jiménez
DESCRIPTION:Professional Organizations and Social Responsibility in Chemical Engineering Education \nProfessional organizations (POs) are established communities that significantly influence the competencies and values of engineers\, but the impact of their interaction with academia on undergraduate education is not fully understood. This study addresses this gap by exploring how engineering faculty in POs strategically incorporate social responsibility into their teaching. Relying on Paulo Freire’s critical consciousness and the Transformational Agency framework\, it examines faculty reflections on societal and power dynamics for curriculum change. \nConducted over eight months\, the study focuses on a Community of Practice (CoP) within the American Institute of Chemical Engineering’s Education Division\, engaging faculty from multiple institutions. We employed qualitative methods\, analyzing interview data through thematic analysis with In-Vivo and Axial coding. Preliminary results highlight how the CoP influences faculty’s reflective practices and understanding of societal structures\, suggesting it enhances educators’ critical awareness and ability to integrate social responsibility into their teaching. \nThe findings deepen our understanding of POs’ role in evolving engineering education. They showcase how educators’ involvement in POs can shape socially responsible engineers\, addressing the complex societal roles engineers face. This seminar aims to inspire educators with strategies for creating transformative learning environments. \n\nDr. Rivera-Jiménez is an Assistant Professor in the Department of Engineering Education at the University of Florida and is affiliated with the Department of Chemical Engineering and the Institute of Higher Education. Her research group focuses on community-driven methods to improve practices and policies that enhance the professional formation of engineers and impact the success of diverse engineering communities\, including faculty\, undergraduate and graduate students\, and transfer students. Current projects include faculty support via professional societies\, student motivation and emotions in blended learning\, and studying diverse transfer student success within organizational contexts. \nAdditionally\, she hosts “The Engineering Professor Speaks Education Podcast\,” a bilingual series exploring the nuances of being an effective engineering educator. Her most recent accolades include the AIChE IDEAL Star Award (2021)\, the AIChE Education Division Service Award (2022)\, and the ASEE Education Research Methods Apprentice Faculty Grantee Award (2023).
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-dr-sindia-m-rivera-jimenez/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240327T120000
DTEND;TZID=America/New_York:20240327T130000
DTSTAMP:20260414T124531
CREATED:20240307T180833Z
LAST-MODIFIED:20240307T180901Z
UID:4809-1711540800-1711544400@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Dr. Christina Chan
DESCRIPTION:Role of microenvironment on mediating diseases\, DNA repair\, and lipid alterations \nOur group incorporates metabolic engineering and systems biology approaches in combination with biochemical and molecular biology measurements to identify targets and disease biomarkers. To modulate these targets and pathway we are concomitantly developing polymeric-based drug delivery systems. \nWe apply a multifaceted approach in investigating the role of soluble cues (e.g.\, elevated fatty acid levels\, PFAS) in the microenvironment on modulating the signaling and regulatory pathways that contribute to diseases. These extracellular signals are mainly in the form of soluble factors that activate intracellular signaling cascades that drive changes in the cell. Our group has identified that saturated fatty acids (i.e.\, palmitate)\, which are well studied for their roles in metabolism\, can also activate signaling pathways that affect proteostasis. Through biochemical and biophysical studies\, we found that palmitate binds directly to proteins involved in proteostasis to modulate their activity and downstream signaling to alter DNA repair\, which has implications on chemotolerance\, lipid profile\, and heart disease. \n\nChristina Chan is a University Distinguished Professor and Interim Chairperson of Chemical Engineering at Michigan State University (MSU). She also has appointments in the Departments of Biochemistry and Molecular Biology\, Biomedical Engineering\, and Computer Science and Engineering. Prior to joining MSU in 2002\, she was a post-doctoral fellow at the Center for Engineering in Medicine at the Harvard Medical School. Chan earned her B.S. in Chemical Engineering from Columbia University and her M.S. and Ph.D. in Chemical and Biochemical Engineering from the University of Pennsylvania. She spent 8 years in DuPont prior to returning to academia. Her laboratory applies a multifaceted approach in investigating the role of soluble cues in the microenvironment on modulating the signaling and regulatory pathways that contribute to diseases. To modulate these targets and pathways\, her laboratory is developing polymeric-based drug delivery systems as well as tissue engineering platforms that capitalize on how scaffolds\, cells\, and biologically active molecules interact to form functional tissues. Her group has published more than 165 journal articles\, reviews\, book chapters and reviewed conference papers. She was elected Fellow of the American Institute of Medical and Biological Engineering (AIMBE)\, AIChE\, and AAAS.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-dr-christina-chan/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240314T110000
DTEND;TZID=America/New_York:20240314T130000
DTSTAMP:20260414T124531
CREATED:20240305T150058Z
LAST-MODIFIED:20240305T150058Z
UID:4805-1710414000-1710421200@che.nucoe.madebyvital.com
SUMMARY:Breaking the Glass Lab
DESCRIPTION:In celebration of Women’s History Month\, join us for a lunch and panel discussion on Breaking the Glass Lab: Understanding the Realities Faced by Women in STEM Higher Education. \nHosted by Bioengineering and Mechanical & Industrial Engineering. \nRegister
URL:https://che.nucoe.madebyvital.com/event/breaking-the-glass-lab/
LOCATION:Fenway Center\, 77 St. Stephen Street\, Boston\, MA\, 02115\, United States
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240313T120000
DTEND;TZID=America/New_York:20240313T130000
DTSTAMP:20260414T124531
CREATED:20240229T165457Z
LAST-MODIFIED:20240229T165457Z
UID:4790-1710331200-1710334800@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Dr. Michael Murrell
DESCRIPTION:Energetic Constraints on Biological Assembly and Motion \nOn small length-scales\, the mechanics of soft materials may be dominated by their interfacial properties as opposed to their bulk properties. These effects are described by equilibrium models of elasto-capillarity and wetting. In these models\, interfacial energies and bulk material properties are held constant. However\, in biological materials\, including living cells and tissues\, these properties are not constant\, but are ‘actively’ regulated and driven far from thermodynamic equilibrium. As a result\, the constraints on work produced during the various physical behaviors of the cell are unknown. Here\, by measurement of elasto-capillary effects during cell adhesion\, growth\, and motion\, we demonstrate that interfacial and bulk parameters violate equilibrium constraints and exhibit anomalous effects\, which depend upon a distance from equilibrium. However\, their anomalous properties are reciprocal\, and thus in combination reliably define energetic constraints on the production of work arbitrarily far from equilibrium. These results provide basic principles that govern biological assembly and behavior. \n\nMichael Murrell received his BS at Johns Hopkins University and his PhD at MIT. He then had a joint postdoctoral fellowship between the Institute for Biophysical Dynamics at the University of Chicago\, and the Institut Curie\, in Paris\, France. He now runs the Laboratory for Living Matter within the Systems Biology Institute at the Yale West Campus\, as part of the Biomedical Engineering and Physics Departments. His laboratory studies the non-equilibrium properties of biological systems\, as well as designs and engineers novel bio-inspired materials. His group comprises a diverse group of experimentalists\, computational scientists\, and theorists all driven to understand some of the most fundamental questions in biophysics.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-dr-michael-murrell/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240305T100000
DTEND;TZID=America/New_York:20240305T110000
DTSTAMP:20260414T124531
CREATED:20240213T213923Z
LAST-MODIFIED:20240215T180413Z
UID:4766-1709632800-1709636400@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Graduate Programs Open House
DESCRIPTION:You are invited to attend The Chemical Engineering Graduate Programs Open House on Tuesday\, March 5 from 10:00am-11:00am on Zoom! This is an exciting way to learn about the different programs and research areas from our Academic Coordinator and Associate Director of MS Programs. Come explore all the opportunities available in the Chemical Engineering department including co-op\, research\, and student groups! \nIf you are interested in applying\, Graduate School of Engineering admissions representatives can provide you with more information on the Double Husky Scholarship\, a 25% tuition discount for NU alumni\, and the Double Husky Quick Application. When you utilize this application\, you are not required to submit GRE scores\, letters of recommendation\, or an application fee. \nPlease join our Zoom session.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-graduate-programs-open-house/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240223T120000
DTEND;TZID=America/New_York:20240223T130000
DTSTAMP:20260414T124531
CREATED:20240208T145057Z
LAST-MODIFIED:20240216T170414Z
UID:4729-1708689600-1708693200@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Jason E. Bara
DESCRIPTION:Sustainability through Plastic Upcycling and Molecular Design of Green Solvents \nThis talk will give overviews of two relatively new research areas in the group of Prof. Jason E. Bara. First\, efforts in plastic waste depolymerization and upcycling will be discussed with a focus on progress that is being made in two particularly challenging materials: poly(vinyl chloride) (PVC) and polyurethanes (PU). As PVC is the 3rd-most produced plastic worldwide\, it is also very different than other commodity polyolefins including polyethylene (PE) and polypropylene (PP). PVC offers unique opportunities for chemistry (via depolymerization and functionalization) as well as solubility behaviors which enable it to be fractionated which can be advantageous and enable new applications for waste PVC\, including 3D printing. Bara’s group is also developing a new process dubbed “imidazolysis” which can break down crosslinked PU materials with recovery of small molecules. With respect to the design of green solvents\, this talk will illustrate how Bara and collaborators are utilizing molecules with glycerol “skeletons” to tackle challenges in CO2 capture (including direct air capture (DAC))\, batteries\, plastic wastes\, additive manufacturing\, and extractions of lithium and other critical materials from dilute sources. \n\nJason received a B.S. in Chemical Engineering from Virginia Commonwealth University and a Ph.D. in Chemical Engineering from the University of Colorado at Boulder. He has authored more than 160 peer-reviewed research publications on the topics of separations\, ionic liquids\, polymer membranes\, and chemical process engineering. He has also been awarded 15 U.S. patents for new technologies developed in these areas. In recognition of his research\, he received the Permeance Prize for Mid-Career Excellence from the North American Membrane Society (NAMS) (2024)\, Early Career Fellow from the Industrial & Engineering Chemistry Division of ACS (2021)\, the Membranes (MDPI) Young Investigator Award (2020) and the FRI/John G. Kunesh Award from the Separations Division of AIChE (2015). Jason has also been recognized for his contributions to chemical engineering education as the 2018 recipient of the Ray W. Fahien Award from ASEE and the 2017 recipient of the David Himmelblau Award for Innovations in Computer-Based Chemical Engineering Education Award from AIChE. \nZoom Link
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-jason-e-bara/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240221T120000
DTEND;TZID=America/New_York:20240221T133000
DTSTAMP:20260414T124531
CREATED:20240202T113619Z
LAST-MODIFIED:20240213T191838Z
UID:4700-1708516800-1708522200@che.nucoe.madebyvital.com
SUMMARY:National Engineers Week: Rewrite the Code - Ignite Innovation with Inclusivity through the Power of Psychological Safety
DESCRIPTION:Fireside Chat on the Power of Psychological Safety with Award-Winning Engineer and Industry Consultant Dr. Mark McBride-Wright and Northeastern’s College of Engineering Dean Gregory Abowd. \n\nLearn how inclusivity in the workplace and beyond can ensure mental and physical safety.\nUnderstand how to use DEI to maximize skillsets.\nExplore impactful case studies increasing representation of minoritized groups in engineering.\nDiscover DEI strategies to enhance productivity and safety in teams.\nTransform the way you lead in all areas of your life.\n\n  \nDate: Wednesday\, February 21\, 2024 \nTime: 12 noon—1:30 p.m.\, ET\, Doors open at 11:30 a.m.\, Complimentary Lunch. \nPlace: Northeastern University\, Fenway Center (77 St Stephen St\, Boston\, MA 02115) and Virtual \nWho: Students\, Faculty\, and Staff\, engineers and non-engineers across Northeastern and other universities \n  \nDr. Mark McBride-Wright is Founder and Managing Director of EqualEngineers\, a company offering a wide array of diversity & inclusion consultancy and training services for corporations\, as well as creative events. He has worked with many Fortune 50 companies. \nAs a recognized diversity and inclusion leader\, he is the recipient of the prestigious Rooke Award from the Royal Academy of Engineering in July 2022 for his work in promoting in engineering to the public. In June 2023\, he was awarded an MBE for services to Diversity\, Equity and Inclusion in the King’s Birthday Honours. He is a Visiting Professor of Inclusive Engineering Leadership at University College London\, and author of the book\, The SAFE Leader© (due for release in March 2024). \nRegister \nEngineers Week
URL:https://che.nucoe.madebyvital.com/event/national-engineers-week-rewrite-the-code-ignite-innovation-with-inclusivity-through-the-power-of-psychological-safety/
LOCATION:Fenway Center\, 77 St. Stephen Street\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240221T120000
DTEND;TZID=America/New_York:20240221T130000
DTSTAMP:20260414T124531
CREATED:20240205T205516Z
LAST-MODIFIED:20240205T205516Z
UID:4723-1708516800-1708520400@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Prashun Gorai
DESCRIPTION:A Journey from Atoms to Materials: Designing Functional Materials for Energy and Microelectronics \nTechnological developments often rely on specifically designed materials and molecules. The increasing pace of technology development\, coupled with rising energy needs and climate challenges\, requires faster approaches for materials discovery. Historically\, materials have been discovered by trial-and-error approaches that rely on chemical intuition. Designing materials with tailored properties is challenging because of the astronomical number of possible compounds and structures\, and materials behaviors that do not adhere to standard chemical intuition. \nComputations have made great strides in accelerating materials development\, but many challenges remain. We are addressing some of these challenges\, including inverse materials design and bridging the gap between theoretical predictions and real materials. In this talk\, I will share examples from our work on the computational discovery and design of functional materials\, as well as modeling of defect and doping properties of semiconductors. \n\nDr. Prashun Gorai is a research assistant professor at the Colorado School of Mines (CSM) with a joint appointment at the National Renewable Energy Laboratory (NREL). He obtained his bachelor’s degree in Chemical Engineering from IIT Madras (India)\, and his PhD\, also in Chemical Engineering\, from the University of Illinois at Urbana-Champaign. He was a postdoctoral fellow at CSM and NREL between 2014-2017. His research team uses quantum-chemical calculations\, high-throughput computing\, and machine learning to discover and design functional materials for energy conversion and storage\, and next-generation microelectronics. The International Thermoelectric Society awarded him the Young Investigator Award in 2022 and the Royal Society of Chemistry (Materials Horizons) recognized him as an Emerging Investigator in 2020. He is a recipient of the Chemistry of Materials Lectureship and Best Paper Award 2023.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-prashun-gorai/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240216T120000
DTEND;TZID=America/New_York:20240216T130000
DTSTAMP:20260414T124531
CREATED:20240205T205415Z
LAST-MODIFIED:20240205T205415Z
UID:4720-1708084800-1708088400@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Adam Caparco
DESCRIPTION:Protein-based materials for sustainable bioprocesses \nProtein materials\, whose function can be programmed by their amino acid sequence\, possess the potential to address many societal challenges by providing a sustainable and biocompatible alternative to many traditional materials. As an example\, the enhancement of enzymes for biocatalysis serves as a gateway for more sustainable chemical manufacturing. I will demonstrate that by designing an enzyme to fuse to a solid support material\, we can vastly improve its stability and recover the material between reactions for multiple uses. Protein materials also serve as a platform for targeted delivery in medicine and agriculture. I will show that by transforming inactivated plant viruses into spherical nanoparticles for encapsulation\, hydrophobic agrochemicals can be delivered through the soil and paralyze roundworms for pest management with high efficacy. \n\nAdam Caparco\, Ph.D. is a postdoctoral scholar at the University of California\, San Diego in the Department of NanoEngineering. His research under Prof. Nicole Steinmetz is funded by a USDA NIFA fellowship and is focused on using plant virus nanoparticles as agricultural delivery systems for pest management and genetic engineering of plants. Prior to this position\, Dr. Caparco completed his doctoral work in Biomolecular Engineering at Georgia Institute of Technology under Profs. Julie Champion and Andreas Bommarius\, where he focused on using self-assembled protein materials for sustainable biocatalysis. During his doctoral studies\, he was awarded a STEM Chateaubriand fellowship and worked with bioinformaticians and biochemists at Genoscope in France. As an undergraduate\, Dr. Caparco studied Chemical and Biomolecular Engineering at the University of California\, Los Angeles.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-adam-caparco/
LOCATION:MA
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240214T120000
DTEND;TZID=America/New_York:20240214T130000
DTSTAMP:20260414T124531
CREATED:20240129T164302Z
LAST-MODIFIED:20240129T164327Z
UID:4685-1707912000-1707915600@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Angela Chen
DESCRIPTION:Engineering Microbial Communication for Sustainable Agriculture \nAgriculture and the global food system accounts for ~30% of greenhouse gas emissions. Therefore\, developing sustainable agricultural technologies is essential for combating and mitigating the effects of climate change. Microbes like bacteria and fungi play pivotal roles in agriculture and food security through complex interactions with plant hosts\, other microorganisms\, and their surroundings. Consequently\, my research aims to investigate how these inter-species and cross-kingdom relationships could be ideal engineering targets for addressing current agricultural challenges. In this seminar\, I will present my work showcasing the power of RNA and nanotechnology in manipulating microbial interactions with the environment and plant hosts. In the first part of my talk\, I will examine how microbes respond to environmental stresses and the use of regulatory RNAs as a genetic platform to manipulate bacterial metal reduction capabilities for the biosynthesis of nanoparticles with unique and enhanced functionality. Following this\, I will then discuss host-microbe interactions and how exploiting RNA-based communication between fungal pathogens and plant hosts can inform next-generation\, nanoparticle-based strategies for plant disease control. Together\, these studies illustrate how understanding and controlling microbial communication will pave the way for new sustainable strategies for reducing agricultural chemical dependence\, improving plant health\, and enabling bioremediation technologies. \n\nAngela Chen is a USDA-NIFA AFRI Postdoctoral Fellow in the Department of Microbiology and Plant Pathology at UC Riverside. Under Prof. Hailing Jin\, she investigates the mechanisms of cross-kingdom RNA trafficking between plants and fungal pathogens to develop nanomaterials for RNAi-based disease control. Prior to UC Riverside\, she received her B.S. in chemical engineering from the Ohio State University and her M.S. and Ph.D. in chemical engineering from the University of Texas at Austin. As an NSF Graduate Research Fellow with Profs. Lydia Contreras and Benjamin Keitz\, she focused on engineering regulatory RNAs in extremophilic bacteria to control bacterial stress response for materials science applications. Outside of research\, Angela is passionate about educating and empowering the next generation of engineers\, having earned a Graduate Certification in Engineering Education. She is also the President of the Riverside Postdoctoral Association\, where she leads initiatives focused on supporting postdocs and broadening STEM access through the creation of diverse and inclusive academic environments.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-angela-chen/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240209T120000
DTEND;TZID=America/New_York:20240209T130000
DTSTAMP:20260414T124531
CREATED:20240205T205600Z
LAST-MODIFIED:20240205T205600Z
UID:4726-1707480000-1707483600@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Leslie Shor
DESCRIPTION:The “Root” of the Nexus: Soil-Based Biotechnology for a Sustainable Future \nThe function of any biological system depends on local environmental conditions. For bacterial systems\, micro-scale structures including the chemical properties and physical topography of surfaces\, micro-scale chemical gradients\, and patterns of biological distribution impact the diversity\, abundance\, and activity of microbial communities. However\, conventional microbial culture systems do not faithfully emulate microbial habitats; thus\, also cannot reflect realistic functionality of microbial systems. The Shor lab designs\, builds\, and operates emulated microbial habitats to better understand microbial system function. Recent applications include soil-emulating micromodels to accelerate the development of agriculture biotechnology. Emulated soil micromodels (ESMs) systematically replicate physical\, chemical\, and biological features while at the same time enabling direct\, real-time observation of biological responses. ESMs enable systematic hypothesis-driven research of rhizosphere processes and make the development of agriculture biotechnology less time-consuming\, expensive\, and difficult. Our work has shown that the microbe-extracellular matrix system in porous media can double evaporative resistance and dramatically improve system resiliency\, but this functionality is only realized in realistic pore-scale geometries. We have also used ESMs to screen microbes for sustainable agriculture applications and shown viable performance in subsequent full-scale testing. With the loom of climate change and its increasing demands on our water and food systems\, there will be rapidly-increasing demand for more productive and cost-effective sustainable agriculture technology\, including food production technology that also provides reliable and safe terrestrial carbon sequestration. This talk will illustrate how fundamental chemical engineering concepts and methods applied to soils can make important contributions towards a more sustainable future. \n\nLeslie Shor mentors an interdisciplinary team working at the intersection of chemical engineering\, microbiology\, and advanced manufacturing. The focus of her research work is developing biotechnology based on soil microbes to enhance sustainable food production.\nShe is the PI of an EFRI project on separation and elimination of microplastics from treated wastewater effluent. She is active in education\, mentoring\, and outreach initiatives aimed at increasing diversity in STEM and enhancing human welfare through high-tech innovation. Shor earned her BA in Environmental Sciences and Chemistry (double-major) from the University of Virginia\, and her PhD in Chemical and Biochemical Engineering from Rutgers University. Prior to coming to UConn\, she was a research assistant professor at Vanderbilt University. In 2018 she spent six months at the University of Adelaide in South Australia as a visiting faculty member in the School of Chemical Engineering.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-leslie-shor/
LOCATION:102 ISEC\, 360 Huntington Ave\, 102 ISEC\, Boston\, MA\, 02115\, United States
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240207T120000
DTEND;TZID=America/New_York:20240207T130000
DTSTAMP:20260414T124531
CREATED:20240129T190149Z
LAST-MODIFIED:20240129T190149Z
UID:4691-1707307200-1707310800@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Benjamin Decardi-Nelson
DESCRIPTION:Optimal Control as a Catalyst for Smart and Sustainable Systems \nSustainability is crucial in modern engineering\, particularly in chemical and biological systems. It involves the use of sustainable resources and the development of environmentally friendly\, smart\, and efficient systems that minimize waste and optimize resource use. Central to engineering smart\, sustainable systems is optimal control. However\, integrating optimal control technologies into these systems is challenging due to the complexity of managing large-scale\, constrained\, nonlinear\, and interconnected subsystems\, particularly under uncertain conditions. In this talk\, I will introduce a series of optimal control technologies that contribute to smarter and more efficient systems\, enhancing their sustainability. Specifically\, I will discuss the development and application of (1) model predictive control and (2) reinforcement learning\, which are instrumental in engineering systems that use minimal resources and generate less waste. I will also demonstrate how optimal control is pivotal in advancing sustainable food production in urban areas through the integration of renewable energy and efficient resource management. These advances in optimal control are critical in developing smart\, sustainable systems and are essential for a sustainable future. \n\nBenjamin Decardi-Nelson is an Eric and Wendy Schmidt AI in Science Postdoctoral Fellow in Systems Engineering at Cornell University. Benjamin’s research interest in Process Systems Engineering centers around developing novel computational tools to improve the analysis\, design and control of complex processes and systems\, with the overarching goal of sustainability. Prior to joining Cornell\, he earned his PhD in Process Control from the University of Alberta\, where he developed efficient algorithms and large-scale optimization models for integrated real-time economic optimization and advanced process control of nonlinear process systems. At Cornell\, Benjamin integrates biology-informed AI with optimization to decarbonize future food systems through implicit learning of plant-environment interactions\, and renewable energy integration. His work has been recognized by the Schmidt AI in Science postdoctoral fellowship\, Natural Sciences and Engineering Research Council of Canada (NSERC) postdoctoral fellowship\, among others.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-benjamin-decardi-nelson/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
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DTSTART;TZID=America/New_York:20240206T120000
DTEND;TZID=America/New_York:20240206T130000
DTSTAMP:20260414T124531
CREATED:20240129T165206Z
LAST-MODIFIED:20240129T165206Z
UID:4688-1707220800-1707224400@che.nucoe.madebyvital.com
SUMMARY:ChemE Department Town Hall
DESCRIPTION:Join Chair and Professor Rebecca Willits of the Chemical Engineering Department as she provides updates and information about classes and the Department of Chemical Engineering.
URL:https://che.nucoe.madebyvital.com/event/cheme-department-town-hall/
LOCATION:MA
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240131T120000
DTEND;TZID=America/New_York:20240131T130000
DTSTAMP:20260414T124531
CREATED:20240123T152555Z
LAST-MODIFIED:20240123T152555Z
UID:4681-1706702400-1706706000@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Professor Bryan James
DESCRIPTION:Design strategies to minimize the environmental impacts of plastic products \nCombatting the existential threats of climate change and pollution requires circularizing and decarbonizing material lifecycles\, reducing persistence\, and eliminating the toxicity of products and processes. Plastics\, the combination of polymer and chemical additives\, contribute significantly to both threats. Despite these harms\, plastics are crucial materials for modern society. In their recent report\, the U.S. National Academies of Sciences\, Engineering\, and Medicine identified material and product design as one of six key interventions to tackle plastic pollution. With this charge\, I will demonstrate how combining concepts learned from the last decade of plastic pollution research with established material selection practices resulted in a quantitative\, multi-dimensional framework for use during product design to minimize the environmental impacts of plastic. By taking this approach\, a sustainability metric was developed for the design of plastic products with low environmental persistence and uncompromised performance. Applying this methodology to commonly littered plastic products (drinking straws and coffee cup lids) demonstrated that accounting for persistence in product design could reduce the societal impacts of plastic pollution by hundreds of millions of dollars for a single product. My findings identify the materials and their properties that deserve development\, adoption\, and investment to create functional and less environmentally impactful plastic products. \n\nDr. Bryan D. James is a Postdoctoral Investigator at the Woods Hole Oceanographic Institution (WHOI). As part of an interdisciplinary team of scientists and engineers within WHOI’s Microplastics Initiative\, his postdoctoral research focuses on understanding the fate\, persistence\, and toxicity of plastic in the ocean to inform the rational design of next-generation materials that are safe for people and the planet. Through this work\, Bryan has collaborated globally with academic colleagues\, NGOs\, and industrial partners and regularly engages with K-12 educators\, mentors community college students\, and advises policymakers. Bryan received his B.A.Sc. in materials engineering from the University of Toronto and his Ph.D. in materials science and engineering from the University of Florida (UF). At UF\, as an NIH F31 Predoctoral Fellow under the mentorship of Prof. Josephine Allen\, Bryan pioneered the use of nucleic acid-collagen complexes for hard and soft tissue engineering and championed investigating sex as a biological variable in biomaterials research\, identifying mechanobiological sex differences in vascular cells. Bryan has been recognized with multiple early career honors and awards\, including being named a Rising Star in Engineering in Health\, a CAS Future Leader\, a DYSS speaker\, and an ACS PMSE Future Faculty Scholar.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-professor-bryan-james/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
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DTSTART;TZID=America/New_York:20240124T100000
DTEND;TZID=America/New_York:20240124T120000
DTSTAMP:20260414T124531
CREATED:20240116T153137Z
LAST-MODIFIED:20240116T153137Z
UID:4667-1706090400-1706097600@che.nucoe.madebyvital.com
SUMMARY:CHE PhD Dissertation Defense: Shicheng Yang
DESCRIPTION:PhD Dissertation Defense: Drug Delivery Systems in Oncology: From Polymeric Implants to Nanomedicine Approaches \nShicheng Yang \nLocation: Hastings Hall 107 & Zoom \nAbstract: Molecular inhibitors\, including PARP inhibitor talazoparib\, CDK inhibitor dinaciclib\, and docetaxel\, are critical in precision cancer therapy\, offering novel therapeutic options for a range of cancers. While demonstrating potent activity as monotherapy or in combination in both preclinical and clinical settings\, challenges such as drug resistance and off-target toxicity persist with these small molecule drugs. To mitigate these issues\, innovative formulation strategies using implants or nanoparticles have been explored. These formulations are designed to alter drug uptake pathways\, resist the emergence of drug resistance\, and minimize direct contact with healthy tissues\, thereby reducing toxicity. This thesis encompasses several nanotechnology approaches in formulating chemotherapy agents and their application across various cancers\, including breast\, ovarian\, pancreatic\, lung\, and prostate. \nIn the context of ovarian cancer\, known for its high mortality rate within the realm of female reproductive system cancers\, more than 15% of cases involve defective BRCA-mediated homologous recombination repair pathways. Talazoparib\, a PARP inhibitor\, has been hindered in its clinical application due to severe systemic side effects. The development of a novel TLZ-loaded PLGA implant (InCeT-TLZ) is reported\, designed for sustained release over 25 days directly into the peritoneal cavity\, targeting BRCA-mutated metastatic ovarian cancer. Results from in vivo experiments indicated a doubling of survival in the InCeT-TLZ treated group compared to controls\, with no significant toxicity observed in surrounding peritoneal organs. This suggests that localized and sustained delivery of Talazoparib can enhance therapeutic efficacy without significant toxicity. Additionally\, the potential of combining CKD inhibitor and PI3K inhibitor with InCeT-TLZ to counteract acquired PARPi resistance was demonstrated in vitro\, indicating a promising approach for enhanced ovarian cancer treatment. \nWhile the biodegradable PLGA implants showed potency\, the conventional solvent-based fabrication methods used to synthesize these implants\, however\, the use of toxic organic solvent and its safety issue pose difficulties for translation to clinical use. To address these challenges\, a scalable\, solvent-free hot-melt extrusion process was introduced for producing PLGA implants iii with docetaxel. This process ensures uniform dispersion of clinically relevant concentrations of the drug without requiring organic solvents. Results showed the bioactivity of incapsulated docetaxel was maintained during fabrication and controlled degradation\, enhancing tumor growth inhibition capabilities both in vitro and in vivo. The implants\, when used intratumorally\, act as both radiosensitizers and continuous chemotherapy sources\, suitable for scale-up in compliance with Good Manufacturing Practices (GMP). \nFurthermore\, the combination of talazoparib and dinaciclib has been studied to overcome PARPi resistance in tumors. The short blood circulation time of dinaciclib and the high toxicity of combination therapies pose significant challenges. Nanomedicine formulations have been developed to address these issues\, creating a nano-cocktail of talazoparib (nTLZ) and dinaciclib (nDCB) to enhance therapeutic efficacy at lower doses. The study showed that these nanoformulations effectively infiltrate tumor cells\, with synergistic effects observed in both BRCAmutant and BRCA wild-type cancer strains\, particularly sensitizing BRCA wild-type cells to PARPi therapy. This approach demonstrates the potential of nanoformulations in broadening the applicability and enhancing the efficacy of combination cancer therapies.
URL:https://che.nucoe.madebyvital.com/event/che-phd-dissertation-defense-shicheng-yang/
LOCATION:MA
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240123T100000
DTEND;TZID=America/New_York:20240123T110000
DTSTAMP:20260414T124531
CREATED:20240116T152955Z
LAST-MODIFIED:20240116T153008Z
UID:4662-1706004000-1706007600@che.nucoe.madebyvital.com
SUMMARY:CHE PhD Dissertation Defense: Jiaming Xu
DESCRIPTION:PhD Dissertation Defense: Molecular simulations of confined deep eutectic solvents for gas separations and liposomes for drug delivery \nLocation: ISEC 332 & Microsoft Teams \nAbstract: This dissertation leverages molecular dynamics simulations to explore the properties of nanoscale materials and interfaces involving gases\, liquids and solids\, traversing the realms of environmental and biological science. This work not only demonstrates the expansive applicability of MD simulations across various scientific disciplines but also highlights their capability to provide profound insights into diverse scientific phenomena. In the segment dedicated to deep eutectic solvents\, our study investigates the behavior of ethaline (mixtures of choline chloride with ethylene glycol at different molar ratios) confined in graphite and titania (rutile) slit pores\, measuring 2 nm and 5 nm in width. This research aims to address the high viscosity issue prevalent in these solvents when saturated with CO2. The results reveal that modifications in the ethylene glycol ratio\, variations in pore sizes\, and the choice of pore wall materials significantly affect the efficiency of CO2/CH4 separation. These findings offer a deeper understanding of how molecular interactions and structural changes in confined spaces can influence the physical properties of DES. \nThe dissertation also delves into the domain of liposomes (nanoparticles formed by a lipid bilayer encapsulating an aqueous core)\, examining the influence of lipid composition and the integration of two distinct small-molecule hydrophobic drugs on their mechanical\, spatial\, and fluid properties. The study encompasses an analysis of the effects of acyl chain saturation and length\, diverse lipid headgroups\, and drug incorporation. Experimental validations\, conducted in collaboration with Prof. Auguste’s laboratory\, support our simulation findings. We discovered that lipids with short-saturated acyl chains and varied headgroups alter the lipid bilayer packing\, resulting in decreased liposome stiffness\, which has been shown promoted drug delivery efficiency. Additionally\, specific drug substances were observed to lower interaction energies within the lipid matrix\, which consequently reduces stiffness and enhances lipid molecule diffusion. This segment of the dissertation provides crucial insights into the design of liposomal formulations\, particularly for drug delivery purposes\, by demonstrating how lipid structure and drug interactions can be manipulated to optimize liposome properties. Overall\, this dissertation underscores the versatility of molecular dynamics simulations in elucidating complex material behaviors and offers valuable contributions to the various engineering fields.
URL:https://che.nucoe.madebyvital.com/event/che-phd-dissertation-defense-jiaming-xu/
LOCATION:MA
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BEGIN:VEVENT
DTSTART;TZID=America/New_York:20240117T120000
DTEND;TZID=America/New_York:20240117T130000
DTSTAMP:20260414T124531
CREATED:20240116T153558Z
LAST-MODIFIED:20240116T153558Z
UID:4671-1705492800-1705496400@che.nucoe.madebyvital.com
SUMMARY:Chemical Engineering Spring Seminar Series: Professor Hongfei Lin
DESCRIPTION:Towards Holistic Approach for Decarbonizing Energy System \nDecarbonizing the energy system is essential for mitigating climate change by replacing fossil fuels with alternative sources emitting significantly less carbon dioxide. Recognizing that no single alternative energy source can meet global demand\, our approach involves utilizing multiple sources for a future carbon-neutral energy system. We focus on developing highly selective and efficient catalytic processes to convert diverse carbon feedstocks\, including renewable and waste carbons. In this seminar\, I will showcase our groundbreaking biphasic tandem catalytic processes\, achieving exceptional carbon-atom efficiencies in converting renewable biomass into biofuels. Additionally\, our innovative sequential catalytic process enables highly selective deconstruction of mixed waste plastics into valuable monomers and fuels. The presentation will also delve into the synergy of integrating direct air capture of CO2 for its utilization in producing value-added carbon-neutral products. Ultimately\, our research aims to implement a holistic approach\, decarbonizing the energy system\, and establishing a sustainable supply of low-carbon intensity chemicals\, materials\, and fuels from renewable and waste carbon resources. \n\nDr. Hongfei Lin is a Professor at the Voiland School of Chemical Engineering and Bioengineering at Washington State University and Chief Scientist in the Energy and Environment Directorate at Pacific Northwest National Laboratory. He earned his B.E. and M.S. degrees from Tsinghua University\, completed his Ph.D. in Chemical Engineering at Louisiana State University\, and further honed his expertise as a postdoctoral fellow at the University of California\, Santa Barbara. With nearly two decades of multidisciplinary research experience\, Dr. Lin focuses on catalysis and sustainability\, particularly in developing novel catalytic processes to derive value-added fuels and chemicals from renewable and waste carbon resources. His commitment to a sustainable\, low-carbon\, circular economy is evident through his numerous publications\, multiple patents\, and extensive support from entities such as DOE\, NSF\, and USDA. Dr. Lin actively contributes to the academic community\, serving on the international advisory board of Energy Technology\, the editorial board of Advanced Composites and Hybrid Materials\, and previously as the Program Chair of the Energy and Fuels Division of the American Chemical Society.
URL:https://che.nucoe.madebyvital.com/event/chemical-engineering-spring-seminar-series-professor-hongfei-lin/
LOCATION:103 Churchill\, 103 Churchill Hall\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
CATEGORIES:use the department, audience, and topic lists
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DTSTART;TZID=America/New_York:20230613T173000
DTEND;TZID=America/New_York:20230613T191500
DTSTAMP:20260414T124531
CREATED:20230522T141116Z
LAST-MODIFIED:20230616T221211Z
UID:4465-1686677400-1686683700@che.nucoe.madebyvital.com
SUMMARY:Ignorance Is Bliss: A Career Retrospective
DESCRIPTION:  \nDean Gregory D. Abowd will present his SIGCHI Lifetime Research Award Acceptance Lecture \nDate: Tues.\, June 13\, 2023 \nTime: 5:30 to 7:15 PM\, reception following Dean Abowd’s talk \nPlace: In-Person and Livestream\nBostonCHI meeting at Northeastern University in ISEC Auditorium (102 ISEC)\, and reception in ISEC Atrium \nRegistration is appreciated but not required. View BostonCHI for more information. \nPresentation Abstract: In 1988\, as a graduate student grappling to find a research identity\, Gregory D. Abowd accidentally discovered the field of Human Computer Interaction (HCI). Over the past 35 years\, he pursued a passion for applying the tools and techniques of computing to uncover how the human experience with technology can be understood and transformed. That leap into HCI was just the first of a number of leaps of faith. Abowd’s career has been a series of shifting research agendas\, each one inspired by some life events. In all cases\, he was buoyed by a bevy of talented and supportive colleagues\, advisors and advisees alike\, who gave him the courage to jump into a research topic that he didn’t know much about. That “ignorance” has allowed him to be more fearless than he had the right to be. In this talk\, Abowd will reflect on his professional journey\, hoping to inspire others to dispel fear of the unknown and unlock their potential. Life\, like research\, is best when shared with others whom you can respect and befriend. \n—————————————— \nGregory D. Abowd\, dean of the College of Engineering and professor of electrical and computer engineering at Northeastern University\, has received the Lifetime Research Award from the Association for Computing Machinery’s (ACM) Special Interest Group on Computer-Human Interaction (SIGCHI). The award is presented to individuals for “the best\, most fundamental\, and influential research contributions to the study of human-computer interaction (HCI)” and is awarded for a lifetime of innovation and leadership. \n 
URL:https://che.nucoe.madebyvital.com/event/ignorance-is-bliss-a-career-retrospective/
LOCATION:102 ISEC\, 360 Huntington Ave\, 102 ISEC\, Boston\, MA\, 02115\, United States
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